陳曜鴻
Professor & Dean, College of Science
Yau-Hung Chen
TEL: (02) 2621-5656 #3009(OFFICE)
#3250(LAB)
Email : yauhung@mail.tku.edu.tw
OFFICE: C104
LAB: C114
Fields of Research
Zebrafish Biology, Developmental Biology, Toxicology, Angiogenesis, and Cancer Biology
Research Expertise
Zebrafish developmental biology, with a focus on bone and skeletal muscle development.
Nephrotoxicity and reproductive toxicity assessment of xenobiotics using zebrafish models.
Identification of genetic and metabolomic biomarkers for renal diseases.
Angiogenesis and vascular biology using zebrafish and chick embryo models.
Tumor–microenvironment interactions and cancer biology.
Current Appointments
Dean, College of Science, Tamkang University
Professor, Department of Chemistry, Tamkang University
Director, Science Education Center, Tamkang University
Academic and Administrative Appointments
2026-present Dean, College of Science, Tamkang University, Taiwan
2025-present Director, Science Education Center, Tamkang University, Taiwan
2019-2023 Chair, Department of Chemistry, Tamkang University, Taiwan
2015-2019 Chair, Bachelor’s Program in Advanced Materials Science, Tamkang University, Taiwan
2010-present Professor, Department of Chemistry, Tamkang University, Taiwan
2009-2010 Associate Professor, Department of Chemistry, Tamkang University, Taiwan
2007-2009 Associate Professor, Graduate Institute of Life Science, Tamkang University, Taiwan
2004-2007 Assistant Professor, Graduate Institute of Life Science, Tamkang University, Taiwan
2003-2004 Postdoctoral Researcher, Institute of Molecular and Cellular Biology, National Taiwan University, Taiwan
2002-2003 Research Associate, Institute of Neuroscience, University of Oregon, Oregon, USA
2001-2002 Postdoctoral Researcher, Institute of Fisheries Science, National Taiwan University, Taiwan
International Research Experience and Visiting Appointments
2025 Visiting Professor, Atomic Bomb Disease Institute, Nagasaki University, Japan (JSPS International Fellow)
2019(July) Short-term Research Visit, University of Massachusetts Lowell, Massachusetts, USA
Higher Education
1997–2001 Ph.D., Institute of Fisheries Science, National Taiwan University, Taiwan
Research focus: Zebrafish Embryology and Developmental Biology
1995–1997 M.S., Institute of Biochemistry, National Taiwan University, Taiwan
Research focus: Gene Regulation
1989–1993 B.S., Department of Medical Technology, National Taiwan University, Taiwan
Selected Publications
Chen YH*, Mohanty B, Li TS, et al. (2026). A phenotype-driven discovery of pro-revascularization chalcone derivatives using zebrafish and CAM models. Journal of Toxicology, 2026: 6939974.
Lee ASY, Lin TH, Liu YY, et al., Chen YH* (2025). Growth inhibition and toxicity assessments of cis-3,4-diaryl-α-methylene-γ-butyrolactams in cultured human renal cancer cells and zebrafish embryos. Biochimica et Biophysica Acta-General Subjects, 1869:130761.
Pan HC#, Chen YH#, Fang WC, Wu VC, Sun CY (2022). Essential roles of the histone demethylase KDM4C in renal development and acute kidney injury. International Journal of Molecular Sciences, 23:9318.
Chen YH*, Chang CY, Chang CF, et al. (2015). Pro-angiogenic effects of chalcone derivatives in zebrafish embryos in vivo. Molecules, 20:12512–12524.
Chen YH*, Chou CY, Sun CY (2015). Impairment of cellular distribution and stability of erythropoietin receptor by direct targeting of aristolochic acid. Toxicological Sciences, 147:246–254.
Chen YH*, Wang WH, Wang YH, Lin ZY, Wen CC, Chern CY (2013). Evaluation of anti-inflammatory effect of chalcone and chalcone analogues in a zebrafish model. Molecules, 18:2052–2060.
Ding YJ, Chen YH* (2012). Developmental nephrotoxicity of aristolochic acid in a zebrafish model. Toxicology and Applied Pharmacology, 261:59–65.
Chen YH*, Yang ZS, Wen CC, et al. (2012). Evaluation of the structure-activity relationship of flavonoids as antioxidants and toxicants of zebrafish larvae. Food Chemistry, 134:717–724.
Lee GH, Chang MY, Hsu CH, Chen YH* (2011). Essential roles of basic helix-loop-helix transcription factors, Capsulin and Musculin, during craniofacial myogenesis of zebrafish. Cellular and Molecular Life Sciences 68: 4065-4078. (Cover article)
Chen YH*, Lin YT, Lee GH (2009). Novel and unexpected functions of zebrafish CCAAT box binding transcription factor (NF-Y) B subunit during cartilages development. Bone, 44:777–784. (Cover article)
Wang YH, Li CK, Lee GH, Tsay HJ, Tsai HJ, Chen YH* (2008). Inactivation of zebrafish mrf4 leads to myofibril misalignment and motor axon growth disorganization. Developmental Dynamics, 237:1043–1050.